Glioblastoma multiforme ( GBM) is the most common and lethal type of brain cancer. 多形性胶质母细胞瘤(GBM)是最常见的致命性的脑部肿瘤。
The most common glioma is glioblastoma multiforme and the possible causes are not fully understood. 最常见的神经胶质瘤为神经胶母细胞瘤,神经胶质瘤形成的因素至今尚未完全明朗。
In the past few years the government has spent$ 100 million dollars for genome studies in lung and ovarian cancers and glioblastoma multiforme, a type of brain tumor. 在过去的几年中,政府为肺癌、卵巢癌、脑胶质母细胞瘤(一种脑组织肿瘤)的基因组研究上投入了1亿美元。
Objective Allelic imbalance ( AI) on chromosome 7 in primary glioblastoma multiforme ( GBM) was detected to locate the chromosomal regions probably associated with the pathogenesis of GBM. 目的研究原发性多形性胶质母细胞瘤7号染色体等位基因失平衡(allelicimbalance,AI)发生率,寻找与胶质母细胞瘤发生、发展可能相关的染色体区域。
Glioblastoma Multiforme is one of the most common primary tumors in the central nervous system in adult that is highly malignant and difficult to treat, whose prognosis is poor. 多形性胶质母细胞瘤是成人常见的颅内原发性肿瘤,呈高度恶性,治疗困难,预后差。
Results: CT appearance of glioblastoma multiforme was low density image, intratumorally apoplexy was high density image. 结果:多形性胶质母细胞瘤CT表现为低密度影,瘤内卒中表现为高密度;
Imaging Diagnosis of Glioblastoma Multiforme 多形性胶质母细胞瘤的影像学诊断
Methods: 21 cases of glioblastoma multiforme were proved by surgical and pathologic findings.20 of them were performed by CT, 18 performed by MRI, analysing the imaging manifestations of them. 方法:经手术病理证实的多形性胶质母细胞瘤21例,其中20例行CT扫描,18例行MRI检查,分别分析其影像学表现。
Results There were 7 cases with anaplastic astrocytoma, 3 cases with glioblastoma multiforme, 1 cases with oligodendroglioma, 1 cases with lower grade glioma. 结果间变性星形细胞瘤7例,多形性胶质母细胞瘤3例,少突胶质瘤1例,低级别胶质瘤1例。
The Potential Correlation between the Size of Peripheral Edema and Prognosis of Glioblastoma Multiforme 脑多形性胶质母细胞瘤水肿带大小与预后相关性的分析
Glioblastoma multiforme had sheet necrosis and large think wall blood vessels. 多形性胶质母细胞瘤可见片状坏死或大量厚壁血管增生。
Glioblastoma Multiforme and Solitary Metastases: Differential Diagnosis by 3T MR Spectroscopic Imaging Conclusion Combining with routine MRI scan, 1H MRS can differentiate the glioma, solitary and atypical cerebral abscess. 结论使用多体素1H-MRS结合常规MRI可鉴别胶质瘤、单发转移瘤、不典型脑脓肿,胶质瘤的瘤细胞可以通过毛细血管转移浸润至瘤周。
The tumor was solitary in 71 cases, and multiple is 3, and the mixed tumor of glioblastoma multiforme and multiple angioreticuloma was located in the temporal lobe in 1 patient, which was rare. 单发者71例,多发者3例,1例颞叶多形性胶质母细胞瘤合并多发性血管网状细胞的混合瘤。
Most patch-like pigmented tumors were glioblastoma multiforme with microvessel density of 77.69 ± 18.28 and mean survival time of 14.9 months. 斑片状浓染型以多形性胶质母细胞瘤为主,微血管密度为77.69±18.28,生存期14.9个月。
Objective To evaluate whether deletion of chromosome 14q is involved in the carcinogenesis of primary glioblastoma multiforme and to identify possibly common deletion regions. 目的评价染色体14q的(杂合性)丢失是否与原发性多形性胶质母细胞瘤的发生发展有关,并确定14q上可能存在的共同杂合性丢失区域。
Study on allelic imbalance of chromosome 7 in primary glioblastoma multiforme 原发性多形性胶质母细胞瘤7号染色体等位基因失平衡状况的研究
The Inhibition of FGF-2 and B7-H1 in the Glioblastoma Multiforme by RNA Interference RNA干扰抑制多型性胶质母细胞瘤FGF-2和B7-H1表达的研究
The prognosis for patients with high-grade gliomas, which include anaplastic astrocytoma ( WHO ⅲ) and glioblastoma multiforme ( GBM, WHO IV), remains dismal. Hence, there is a great hope for novel therapeutic approaches. 并且,高级别胶质瘤(间变型星形细胞瘤WHOm;多形性胶质母细胞瘤WHOW)患者的预后情况依然不佳。因此,临床上期待有更加行之有效的治疗方式。